National Particle Component Toxicity (NPACT) initiative: Study 4. Mortality and long-term exposure to PM2.5 and its components in the American Cancer Society's Cancer Prevention Study II Cohort
Thurston, GD; Ito, K; Lall, R; Burnett, RT; Turner, MC; Kewski, D; Shi, Y; Jerrett, M; Gapstur, SM; Diver, WR; Pope, CA, III
HERO ID
3520341
Reference Type
Technical Report
Subtype
HEI
Year
2013
Language
English
| HERO ID | 3520341 |
|---|---|
| Material Type | HEI |
| Year | 2013 |
| Title | National Particle Component Toxicity (NPACT) initiative: Study 4. Mortality and long-term exposure to PM2.5 and its components in the American Cancer Society's Cancer Prevention Study II Cohort |
| Authors | Thurston, GD; Ito, K; Lall, R; Burnett, RT; Turner, MC; Kewski, D; Shi, Y; Jerrett, M; Gapstur, SM; Diver, WR; Pope, CA, III |
| Publisher Text | Health Effects Institute |
| City | Boston, MA |
| Page Numbers | 127-166 |
| Abstract | Epidemiologic studies conducted over recent decades have shown that long-term exposure to elevated ambient levels of PM2.5* is associated with increased risk of death, especially from ischemic heart disease (IHD) and lung cancer. The earlier analyses of the American Cancer Society’s (ACS) Cancer Prevention Study II (CPS-II) cohort (Pope et al. 1995, 2002, 2004), the largest prospective cohort study, found that mortality from all causes and from cardiopulmonary diseases increased in positive association with the level of ambient PM2.5. However, the components in PM2.5 (e.g., ions, trace metals, organic compounds) and the emission sources of the particles (e.g., coal-fired power plants, residual oil combustion, traffic, soil) that are most closely associated with the increased risk of mortality have yet to be determined. |
| Report Number | 177 |
| Url | https://www.healtheffects.org/system/files/RR177-Lippmann.pdf |
| Is Certified Translation | No |
| Dupe Override | No |
| Number Of Pages | 42 |
| Is Public | Yes |
| Language Text | English |
| Relationship(s) |