Recent advances in synthetic transformations mediated by cerium(IV) ammonium nitrate
Nair, V; Balagopal, L; Rajan, R; Mathew, J
| HERO ID | 3738367 |
|---|---|
| In Press | No |
| Year | 2004 |
| Title | Recent advances in synthetic transformations mediated by cerium(IV) ammonium nitrate |
| Authors | Nair, V; Balagopal, L; Rajan, R; Mathew, J |
| Journal | Accounts of Chemical Research |
| Volume | 37 |
| Issue | 1 |
| Page Numbers | 21-30 |
| Abstract | Cerium(IV) ammonium nitrate (CAN) has recently emerged as a versatile reagent for oxidative electron transfer; the overwhelming number of reports serve as a testimony to the unparalleled utility of CAN in a variety of transformations of synthetic importance. Our recent work has uncovered novel carbon-carbon bond-forming reactions leading to the one-pot synthesis of dihydrofurans, tetrahydrofurans, and aminotetralins. In addition, we have developed a number of facile carbon-heteroatom bond-forming reactions by the CAN-mediated oxidative addition of soft anions to alkenes. A mechanistic rationale has been provided for the reactions explored. As might be expected of very powerful one-electron oxidants, the chemistry of cerium(IV) oxidation of organic molecules is dominated by radical and radical cation chemistry. |
| Doi | 10.1021/ar030002z |
| Pmid | 14730991 |
| Wosid | WOS:000188386100003 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |