Biotransformation of 6:2 fluorotelomer alcohol (6:2 FTOH) by a wood-rotting fungus
Tseng, N; Wang, N; Szostek, B; Mahendra, S
| HERO ID | 3857382 |
|---|---|
| In Press | No |
| Year | 2014 |
| Title | Biotransformation of 6:2 fluorotelomer alcohol (6:2 FTOH) by a wood-rotting fungus |
| Authors | Tseng, N; Wang, N; Szostek, B; Mahendra, S |
| Journal | Environmental Science & Technology |
| Volume | 48 |
| Issue | 7 |
| Page Numbers | 4012-4020 |
| Abstract | Biotransformation of 6:2 FTOH [F(CF2)6CH2CH2OH] by the white-rot fungus, Phanerochaete chrysosporium, was investigated in laboratory studies. 6:2 FTOH is a raw material increasingly being used to replace products that can lead to long-chain perfluoroalkyl carboxylic acids (PFCAs, ≥ 8 carbons). During a product's life cycle and after final disposal, 6:2 FTOH-derived compounds may be released into the environment and potentially biotransformed. In this study, P. chrysosporium transformed 6:2 FTOH to perfluorocarboxylic acids (PFCAs), polyfluorocarboxylic acids, and transient intermediates within 28 days. 5:3 Acid [F(CF2)5CH2CH2COOH] was the most abundant transformation product, accounting for 32-43 mol % of initially applied 6:2 FTOH in cultures supplemented with lignocellulosic powder, yeast extract, cellulose, and glucose. PFCAs, including perfluoropentanoic (PFPeA) and perfluorohexanoic (PFHxA) acids, accounted for 5.9 mol % after 28-day incubation. Furthermore, four new transformation products as 6:2 FTOH conjugates or 5:3 acid analogues were structurally confirmed. These results demonstrate that P. chrysosporium has the necessary biochemical mechanisms to drive 6:2 FTOH biotransformation pathways toward more degradable polyfluoroalkylcarboxylic acids, such as 5:3 acid, with lower PFCA yields compared to aerobic soil, sludge, and microbial consortia. Since bacteria and fungi appear to contribute differently toward the environmental loading of FTOH-derived PFCAs and polyfluorocarboxylic acids, wood-rotting fungi should be evaluated as potential candidates for the bioremediation of wastewater and groundwater contaminated with fluoroalkyl substances. |
| Doi | 10.1021/es4057483 |
| Pmid | 24593855 |
| Wosid | WOS:000333776100050 |
| Url | https://search.proquest.com/docview/1514849448?accountid=171501 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Environmental Studies; Cellulose; Glucose; Bacteria; Groundwater |