Percutaneous toxicity of ethylene glycol monomethyl ether and of dipropylene glycol monomethyl ether in the rat
Fairhurst, S; Knight, R; Marrs, TC; Scawin, JW; Spurlock, MS; Swanston, DW
HERO ID
4146480
Reference Type
Journal Article
Year
1989
Language
English
PMID
| HERO ID | 4146480 |
|---|---|
| In Press | No |
| Year | 1989 |
| Title | Percutaneous toxicity of ethylene glycol monomethyl ether and of dipropylene glycol monomethyl ether in the rat |
| Authors | Fairhurst, S; Knight, R; Marrs, TC; Scawin, JW; Spurlock, MS; Swanston, DW |
| Journal | Toxicology |
| Volume | 57 |
| Issue | 2 |
| Page Numbers | 209-215 |
| Abstract | The subacute percutaneous toxicity of dipropylene glycol monomethyl ether (DPM) in male rats dosed 5 days/week for 4 weeks under both occluded and unoccluded conditions has been assessed and compared to the percutaneous toxicity of ethylene glycol monomethyl ether (EGM). DPM caused no significant changes in the clinical chemistry, haematology, or pathology, whereas EGM caused changes in the haematology and clinical chemistry, and both testicular and bone marrow damage at doses of 1000 mg/kg per day. |
| Doi | 10.1016/0300-483X(89)90166-2 |
| Pmid | 2749747 |
| Wosid | WOS:A1989AG18900006 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Relationship(s) |
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