Prescription drugs among pregnant women in Lome, Togo, West Africa
Potchoo, Y; Redah, D; Gneni, MA; Guissou, IP
HERO ID
4850126
Reference Type
Journal Article
Year
2009
Language
English
PMID
| HERO ID | 4850126 |
|---|---|
| In Press | No |
| Year | 2009 |
| Title | Prescription drugs among pregnant women in Lome, Togo, West Africa |
| Authors | Potchoo, Y; Redah, D; Gneni, MA; Guissou, IP |
| Journal | European Journal of Clinical Pharmacology |
| Volume | 65 |
| Issue | 8 |
| Page Numbers | 831-838 |
| Abstract | Objective: To assess the trends in prescription drugs and the potential repercussions to newborns among pregnant women who attended prenatal consultations and gave birth in the Department of Gynaecology of Tokoin’s University Hospital, Lome (Togo). Methods: A retrospective study of the registers of prenatal visits and deliveries of the eligible population was performed. Results: In total, 184 different drugs were prescribed to 627 pregnant women attending prenatal consultations. The profile of pharmacotherapeutic groups prescribed was: anti-anaemics (33.33%), antimalarial drugs (24.75%), vitamins ± mineral salts, amino acids and appetite stimulants (14.96%) and antispasmodics and anti-emetics (7.22%). The median proportion of prescriptions for each pharmacotherapeutic group increased significantly from the first to third trimester (9.72, 25.17 and 64.00 respectively; P < 0.05). The median number of drugs prescribed did not vary significantly (P = 0.051) with the age groups, parity (P = 0.068) or obstetrical–gynaecological history (P = 0.401); it did, however, increase significantly with the medical–surgical history (P < 0.05). There were complications associated with deliveries that had no obvious cause related to drug prescription, including four cases of minor defects, 28 stillborns, 65 cases of low birth weight and 27 hospitalised newborns for neonatal diseases. Some interventions were needed for safeguarding the health of the mother, the foetus and the newborn. Conclusion: The trends in obtaining prescription drugs and the consumption of drugs by pregnant women can be assessed using multiple parameters. We limited our study to age groups, gestational age, parity and the medical history of the pregnant woman, profile of pharmacotherapeutic groups, median number of drugs prescribed and the potential risks of the drugs used. The results of our retrospective study were not alarming in terms of neonatal outcomes. |
| Doi | 10.1007/s00228-009-0644-5 |
| Pmid | 19337728 |
| Wosid | WOS:000268309200011 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Lome Togo; Pharmacology; Prenatal care; Risk factors |
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