Transition-metal-free decarboxylation of dimethyl malonate: an efficient construction of α-amino acid esters using TBAI/TBHP
Zhang, J; Shao, Y; Wang, Y; Li, H; Xu, D; Wan, X
| HERO ID | 4923495 |
|---|---|
| In Press | No |
| Year | 2015 |
| Title | Transition-metal-free decarboxylation of dimethyl malonate: an efficient construction of α-amino acid esters using TBAI/TBHP |
| Authors | Zhang, J; Shao, Y; Wang, Y; Li, H; Xu, D; Wan, X |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 13 |
| Issue | 13 |
| Page Numbers | 3982-3987 |
| Abstract | A transition-metal-free decarboxylation coupling process for the preparation of α-amino acid esters, which succeeded in merging hydrolysis/decarboxylation/nucleophilic substitution, is well described. This strategy uses commercially available inexpensive starting materials, catalysts and oxidants and has a wide substrate scope and operational simplicity. |
| Doi | 10.1039/c5ob00109a |
| Pmid | 25722069 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |