Organocatalytic dynamic kinetic resolution via conjugate addition: synthesis of chiral trans-2,5-dialkylcyclohexanones
Pandey, G; Adate, PA; Puranik, VG
| HERO ID | 4923518 |
|---|---|
| In Press | No |
| Year | 2012 |
| Title | Organocatalytic dynamic kinetic resolution via conjugate addition: synthesis of chiral trans-2,5-dialkylcyclohexanones |
| Authors | Pandey, G; Adate, PA; Puranik, VG |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 10 |
| Issue | 41 |
| Page Numbers | 8260-8267 |
| Abstract | A novel strategy of initiating an organocatalysed dynamic kinetic resolution (dr up to 99 : 1 and er up to 94 : 6) for the synthesis of chiral trans-2,5-dialkylcyclohexanones by an asymmetric conjugate addition of dimethyl malonate on to 6-substituted cyclohexenones is reported. |
| Doi | 10.1039/c2ob26597d |
| Pmid | 22972151 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |