Fat and mesenteric blood flow
Andersen, TC; Pedersen, JF; Nordentoft, T; Olsen, O
HERO ID
4929526
Reference Type
Journal Article
Year
1999
Language
English
PMID
| HERO ID | 4929526 |
|---|---|
| In Press | No |
| Year | 1999 |
| Title | Fat and mesenteric blood flow |
| Authors | Andersen, TC; Pedersen, JF; Nordentoft, T; Olsen, O |
| Journal | Scandinavian Journal of Gastroenterology |
| Volume | 34 |
| Issue | 9 |
| Page Numbers | 894-897 |
| Abstract | <strong>BACKGROUND: </strong>The introduction of fat to the duodenum leads to an increase in mesenteric blood flow. The exact mechanism, however, is unknown. In this study we investigate the influence of the terminal carboxy group of the oleic acid molecule on superior mesenteric artery blood flow.<br /><br /><strong>METHODS: </strong>In six healthy male volunteers duplex ultrasound was used to evaluate the effects of duodenal perfusion of 48 mmol oleic acid and 48 mmol oleyl alcohol on superior mesenteric artery blood flow variables and diameter.<br /><br /><strong>RESULTS: </strong>The blood flow variables time-average velocity and maximal diastolic velocity increased significantly, and the resistance index decreased significantly during perfusion with oleic acid, but during oleyl alcohol perfusion no changes were found. No significant changes in vessel diameter were observed at any time.<br /><br /><strong>CONCLUSION: </strong>The carboxy group of the oleic acid molecule has an important role in the duodenum in mediating the postprandial increase in superior mesenteric artery blood flow. |
| Pmid | 10522608 |
| Wosid | WOS:000082853500010 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | blood flow; duplex ultrasound; fat; oleic acid; oleyl alcohol; superior mesenteric artery |