n-Docosanol 10% cream in the treatment of recurrent herpes labialis: a randomised, double-blind, placebo-controlled study
Habbema, L; De Boulle, K; Roders, GA; Katz, DH
HERO ID
4929588
Reference Type
Journal Article
Year
1996
Language
English
PMID
| HERO ID | 4929588 |
|---|---|
| In Press | No |
| Year | 1996 |
| Title | n-Docosanol 10% cream in the treatment of recurrent herpes labialis: a randomised, double-blind, placebo-controlled study |
| Authors | Habbema, L; De Boulle, K; Roders, GA; Katz, DH |
| Journal | Acta Dermato-Venereologica |
| Volume | 76 |
| Issue | 6 |
| Page Numbers | 479-481 |
| Abstract | n-Docosanol has been shown to have antiviral activity. To demonstrate the efficacy of n-docosanol 10% cream in the treatment of recurrent herpes labialis, a randomised, double-blind, parallel group, placebo-controlled study was undertaken in 63 patients. In a crossover extension, 22 of the patients used the alternative treatment for a further episode. A total of 98 episodes were evaluated. Application of n-docosanol 10% cream early in the prodromal or erythema stage of a recurrent episode of herpes labialis shortened mean healing time by approximately 3 days, as compared to late treatment with n-docosanol 10% cream and early or late treatment with the placebo. The crossover study revealed that late treatment with n-docosanol 10% cream significantly reduced mean healing time compared to placebo. Treatments were well tolerated. |
| Pmid | 8982417 |
| Wosid | WOS:A1996VW02300018 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | antiviral; cold sore; topical application |
| Relationship(s) |
|