Synthesis, Characterization, and Antibacterial Activity of Novel Pyridones
Gezegen, H; Ceylan, M; Karaman, Isa; Sahin, E
| HERO ID | 4932900 |
|---|---|
| In Press | No |
| Year | 2014 |
| Title | Synthesis, Characterization, and Antibacterial Activity of Novel Pyridones |
| Authors | Gezegen, H; Ceylan, M; Karaman, Isa; Sahin, E |
| Journal | Synthetic Communications |
| Volume | 44 |
| Issue | 8 (Apr 18 |
| Page Numbers | 1084-1093 |
| Abstract | Novel ethyl 2-oxo-4,6-diaryl-1,2,3,4-tetrahydropyridine-3-carboxylate and 4,6-diaryl-3,4-dihydropyridine-2(1H)-one derivatives have been synthesized from the cyclization of adducts of diethylmalonate to chalcones with ammonium acetate. The structures were established on the basis of extensive spectroscopic methods and further confirmed by X-ray crystallographic analysis. Antibacterial activity of obtained pyridones was investigated against four human pathogen microorganisms and the compounds showed poor activity. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications registered for the following free supplemental resource(s): Full experimental and spectral details.] |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Keyword | Antibacterial activity; Ionizing radiation; Adducts; Microorganisms; Pathogens; Ammonium acetate; Internet; 2014) |