Catalytic Asymmetric Allenylation of Malonates with the Generation of Central Chirality
Li, Q; Fu, C; Ma, S
| HERO ID | 4933350 |
|---|---|
| In Press | No |
| Year | 2012 |
| Title | Catalytic Asymmetric Allenylation of Malonates with the Generation of Central Chirality |
| Authors | Li, Q; Fu, C; Ma, S |
| Journal | Angewandte Chemie (International Edition) |
| Volume | 51 |
| Issue | 47 (Nov 19 |
| Page Numbers | 11783 |
| Abstract | Water plays an important role in a palladium-catalyzed allenylation of diethyl malonate with 2,3-allenyl acetates to yield centrally chiral allenyl malonates bearing synthetically useful functional groups. The products were formed with 92-96%ee in the presence of a bulky, electron-rich biphenyl ligand at room temperature. |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Keyword | 2012) |