Analysis of bioactive chemical components of two medicinal plants (Coriandrum sativum and Melia azedarach) leaves using gas chromatography-mass spectrometry (GC-MS)
Al-Marzoqi, AH; Hameed, IH; Idan, SA
HERO ID
4933660
Reference Type
Journal Article
Year
2015
Language
English
| HERO ID | 4933660 |
|---|---|
| In Press | No |
| Year | 2015 |
| Title | Analysis of bioactive chemical components of two medicinal plants (Coriandrum sativum and Melia azedarach) leaves using gas chromatography-mass spectrometry (GC-MS) |
| Authors | Al-Marzoqi, AH; Hameed, IH; Idan, SA |
| Journal | African Journal of Biotechnology |
| Volume | 14 |
| Issue | 40 |
| Page Numbers | 2812-2830 |
| Abstract | The main objective of this study was to determine the phytochemical composition in the leaves of Coriandrum sativum, using methanolic extraction and report the main functional components by using IR technique. The phytochemical compounds in the extract were then screened by GC-MS method. Seven bioactive phytochemical compounds were identified in the methanolic extract of C. sativum: 1,6-octadien-3-ol, 3,7-dimethyl, 1,6-octadien-3-ol,3,7-dimethyl, 2-aminobenzoate, bicyclo[2.2.1]heptan-2-one,1,7,7-trimethyl., geranyl vinyl ether, 9,10-secocholesta-5,7,10(19)-triene-3,24,25-triol., ascorbic acid 2,6-dihexadecanoate and 7aH-cyclopenta[a] cyclopropa[f]cycloundecene. Thirteen bioactive phytochemical compounds were identified in the methanolic extract of Melia azedarach. In the present investigation, a variety of compounds have been detected in M. azedarach including trichloromethane, propanedioic acid, diethyl ester, 2-pyrrolidinyl-methylamine, butanedioic acid, diethyl ester, 2-piperidimethanamine, butanedioic acid, hydroxyl-, diethyl ester, 2,5-dimethylhexane-2,5-dihydroperoxide, dithiocarbamate, s-methyl-,n-(2-methyl-3-oxobutyl), triethyl citrate, y-sitosterol, ethyl 9,12,15-octadecatrienoate, hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, and octadecane, 3-ethyl-5-(2-ethylbutyl). It contains chemical constitutions which may be useful for various herbal formulation as anti-inflammatory, analgesic, antipyretic, cardiac tonic and antiasthamatic. C. sativum is highly active against Aspergillus terreus 6.01 plus or minus 0.200. Bioactive compounds of C. sativum and M. azedarach were assayed for in vitro antibacterial activity against Staphylococcus aureus, Proteus mirabilis, Pseudomonas aerogenosa, Escherichia coli and Klebsiella pneumonia using the diffusion method in agar. The zone of inhibition was compared with different standard antibiotics. The diameters of inhibition zones ranged from 5.60 plus or minus 0.320 to 1.96 plus or minus 0.200 mm for all treatments. |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Heart; Agar; Antibacterial activity; Medicinal plants; Leaves; Antibiotics; Esters; Mass spectroscopy; Inflammation; Ascorbic acid; Gas chromatography; Palmitic acid; Acids; Diffusion; Ethers; Analgesics; Biotechnology; Pneumonia; Citric acid; Klebsiella; Coriandrum sativum; Melia azedarach; Escherichia coli; Pseudomonas; Staphylococcus aureus; Aspergillus terreus; Proteus mirabilis; 2015) |