Eye irritation: studies relating to responses in man and laboratory animals

Van Abbe, NJ

HERO ID

4934108

Reference Type

Journal Article

Year

1973

Language

English

HERO ID 4934108
In Press No
Year 1973
Title Eye irritation: studies relating to responses in man and laboratory animals
Authors Van Abbe, NJ
Journal Journal of the Society of Cosmetic Chemists
Volume 24
Issue Oct 14 1973
Abstract IPA COPYRIGHT: ASHP A male hairdressing formulation produced eye irritancy during test marketing despite negative toxicity screening tests in rabbits and squirrel monkeys. The adverse effects were detected during a 10-month test market period, during which 20 complaints of eye irritation were received. This represented 1 complaint for every 8,500 hair preparations sold. Irritation was observed after exposure to rain or snow. The dressing, a solid transparent microemulsion, produced reversible visual blurring, corneal pitting, itching and pain. Similar responses were noted in human volunteers when an aqueous solution of the ethoxylated oleyl alcohol constituent of the dressing was instilled in the eye.
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English