A simple synthesis of 1,1,2-tris-(hydroxymethyl) cyclopropane and its dihalo derivatives
Finta, Z; Hell, Z; Cwik, A; Toke, L
| HERO ID | 4935996 |
|---|---|
| In Press | No |
| Year | 2002 |
| Title | A simple synthesis of 1,1,2-tris-(hydroxymethyl) cyclopropane and its dihalo derivatives |
| Authors | Finta, Z; Hell, Z; Cwik, A; Toke, L |
| Issue | 9 |
| Page Numbers | 459-460 |
| Abstract | The phase transfer catalytic cyclopropa nation of the malonic ester of allylic alcohol or its 3,3-dibromo and 3,3-dichloro derivatives yields bicyclic cyclopropane carboxylic acid lactones; reduction of these lactones with LiAlH4 in boiling THF yields the appropriate 1,1,2-tris-(hydroxymethyl)cyclopropanes in satisfactory yield. |
| Wosid | WOS:000179393500019 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Journal:JOURNAL OF CHEMICAL RESEARCH-S 0308-2342 |
| Is Public | Yes |
| Keyword | cyclopropanes; cyclisation; reduction |