Enantiopure fluorous 1,2-diaryl-1,2-diaminoethanes: synthesis and applications in asymmetric organometallic catalysis
Bayardon, J; Sinou, D
| HERO ID | 4936120 |
|---|---|
| In Press | No |
| Year | 2008 |
| Title | Enantiopure fluorous 1,2-diaryl-1,2-diaminoethanes: synthesis and applications in asymmetric organometallic catalysis |
| Authors | Bayardon, J; Sinou, D |
| Page Numbers | 26-35 |
| Abstract | The synthesis of a new enantiopure fluorous 1,2-diaryl-1,2-diaminoethane bearing two fluorous ponytails is described. The palladium-catalyzed reaction of 1,3-diphenyl-2-propenyl acetate with dimethyl malonate in the presence of this ligand and its analogue bearing four fluorous ponytails gave the alkylated product with ee up to 44%. Their application as ligands in hydrogen transfer reactions associated with rhodium, iridium, or ruthenium in a two-phase system gave ee up to 39%, the catalyst being recycled without loss of enantioselectivity in the case of the ruthenium complex. |
| Wosid | WOS:000260410200004 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Journal:ARKIVOC 1424-6376 |
| Is Public | Yes |
| Keyword | Enantiopure fluorous diamines; asymmetric catalysis; allylic alkylation; hydrogen-transfer reaction |