alpha -Enones in heterocyclic synthesis of indazole, thiazine, chromene and quinoline derivatives with their antimicrobial activities
Sayed, GH; Hemdan, MM; Abd-Elhalim, MS; Sayed, FEM
| HERO ID | 4936820 |
|---|---|
| Year | 2009 |
| Title | alpha -Enones in heterocyclic synthesis of indazole, thiazine, chromene and quinoline derivatives with their antimicrobial activities |
| Authors | Sayed, GH; Hemdan, MM; Abd-Elhalim, MS; Sayed, FEM |
| Publisher Text | Science Reviews 2000 Ltd, Science Reviews 2000 Ltd, 37 Warren Street, London, W1T 6AD |
| Volume | 2009 |
| Page Numbers | 726-728 |
| Abstract | alpha -Enones 1a,b react additively with hydrazine hydrate, thiourea, diethyl malonate, malononitrile, as well as ethyl cyanoacetate. Simultaneous cyclisation of the resulting 1:1 adducts yields indazole, thiazine, chromene and quinoline derivatives. The structures of all the synthesised compounds were confirmed by micro analytical and spectral data. The antimicrobial activity of some of the synthesised compounds were tested. |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Journal:Journal of Chemical Research ISSN:2047-6507 |
| Is Public | Yes |
| Keyword | Antimicrobial activity; Adducts |