Copper(I)-Catalyzed C-C and C-O Coupling Reactions Using Hydrazone Ligands

Mino, T; Yagishita, F; Shibuya, M; Kajiwara, K; Shindo, H; Sakamoto, M; Fujita, T

HERO ID

4937142

Reference Type

Journal Article

Year

2009

HERO ID 4937142
In Press No
Year 2009
Title Copper(I)-Catalyzed C-C and C-O Coupling Reactions Using Hydrazone Ligands
Authors Mino, T; Yagishita, F; Shibuya, M; Kajiwara, K; Shindo, H; Sakamoto, M; Fujita, T
Journal Synlett
Issue 15
Page Numbers 2457-2460
Abstract Copper-catalyzed C-C coupling reaction of aryl iodides with diethylmalonate in toluene at 90 degrees C gave arylated malonates using 5 mol% of Cul with hydrazone 1a as a ligand in good yields under an aerobic atmosphere. We also found Cul/hydrazone 1b in toluene to be an efficient catalytic system for C-O Coupling reactions of aryl bromides with phenols to give aryl ethers ill good yields at 110 degrees C under an aerobic atmosphere.
Doi 10.1055/s-0029-1217822
Wosid WOS:000270593200015
Is Certified Translation No
Dupe Override No
Is Public Yes
Keyword copper catalyst; hydrazone; C-C coupling; C-O coupling; malonate; aryl ether