Microbiological degradation of a synthetic benzofurane type lactone

Solujic, S; Sukdolak, S; Krstic, LJ

HERO ID

4937155

Reference Type

Journal Article

Year

1999

HERO ID 4937155
In Press No
Year 1999
Title Microbiological degradation of a synthetic benzofurane type lactone
Authors Solujic, S; Sukdolak, S; Krstic, LJ
Journal Indian Journal of Chemistry. Section B
Volume 38
Issue 2
Page Numbers 160-165
Abstract A benzofurane type lactone 4 incorporating an alpha-methylene-gamma-butyrolactone moiety has been synthesized. The key steps involved are the Michael condensation of 4-dichloromethyl-4-methyl-2,5-cyclohexadienone 1 with dimethyl malonate and acetoxylation of 4-dichloromethyl-5-carboxymethyl-4-methyl-2-cyclohexenone 2 with lead (IV) acetate in BF3-etherate which are indicative of the general route to gamma-lactone. Microbial degradations of the synthetic benzofurane type lactone 4 have also been studied using Aspergillus niger, Saccharomyces cerevisiae, Bacillus mycoides, Agrobacterium tumefaciens, Pseudomonas glicinea and Pseudomonas fluorescens. The lactone acts both as an additive for the nutrient substrate and as a source of organic carbon.
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