Synthesis of heterospirans containing a gamma-lactone ring

Avetisyan, AA; Tokmadzhyan, GG; Piridzhanyan, RA

HERO ID

4937172

Reference Type

Journal Article

Year

2008

HERO ID 4937172
In Press No
Year 2008
Title Synthesis of heterospirans containing a gamma-lactone ring
Authors Avetisyan, AA; Tokmadzhyan, GG; Piridzhanyan, RA
Journal Russian Journal of Organic Chemistry
Volume 44
Issue 7
Page Numbers 1077-1081
Abstract Reactions of alpha-ketols with diethyl malonate at the molar ratio 2:1 in the presence of K(2)CO(3) were investigated. The heterospiranes obtained contained a dihydrofuran and a gamma-lactone rings. The optimum conditions for the synthesis of heterospiranes were found by varying the ratio of the initial compounds: alpha-ketoalcohol (or 2-ethoxycarbonyl-, 2-methoxycarbonyl-, 2-cyano-3,4,4-trimethyl-2-buten-4-olides), diethyl malonate, K(2)CO(3), by varying the environment, and also the temperature and the time of the reaction.
Doi 10.1134/S1070428008070221
Wosid WOS:000258702100022
Is Certified Translation No
Dupe Override No
Is Public Yes