Origins of neutral sterols in human feces studied by stable isotope labeling (D and 13C). Effect of phytosterols and calcium

Ferezou, J; Sulpice, JC; Coste, T; Chevallier, F

HERO ID

4946605

Reference Type

Journal Article

Year

1982

Language

English

PMID

7160547

HERO ID 4946605
In Press No
Year 1982
Title Origins of neutral sterols in human feces studied by stable isotope labeling (D and 13C). Effect of phytosterols and calcium
Authors Ferezou, J; Sulpice, JC; Coste, T; Chevallier, F
Journal Digestion
Volume 25
Issue 3
Page Numbers 164-172
Abstract A stable isotope labeling (13C and D) was administered to 8 subjects in order to observe the short-term effect of phytosterols (Cytellin 9 g/day) or calcium (calcium gluconate 3 g/day) on the processes involved in cholesterol elimination in the feces. Under control conditions, the mean fraction of fecal cholesterol having a plasmatic origin was 69% and that of cholesterol secreted by the digestive tract 11%. The remaining fraction represented unabsorbed dietary cholesterol. While both treatments reduced the absorption of cholesterol, Cytellin enhanced the fecal excretion of plasma cholesterol and calcium lowered it. The change observed in the rate of intestinal external secretion did not follow the change in the fecal excretion of cholesterol.
Doi 10.1159/000198825
Pmid 7160547
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English