The putative pheromone androstadienone activates cortical fields in the human brain related to social cognition
Gulyás, B; Kéri, S; O'Sullivan, BT; Decety, J; Roland, PE
| HERO ID | 4947202 |
|---|---|
| In Press | No |
| Year | 2004 |
| Title | The putative pheromone androstadienone activates cortical fields in the human brain related to social cognition |
| Authors | Gulyás, B; Kéri, S; O'Sullivan, BT; Decety, J; Roland, PE |
| Journal | Neurochemistry International |
| Volume | 44 |
| Issue | 8 |
| Page Numbers | 595-600 |
| Abstract | Using 15O-butanol positron emission tomography (PET), we measured regional cerebral blood flow changes in five healthy young women during exposure to androstadienone, a putative human pheromone, as well as pleasant (gamma-methyl-ionone), unpleasant (methyl-thio-butanoate), and neutral (dipropylene glycol; vehicle compound) odours. Compared with the odorous substances, androstadienone activated a widely distributed neuronal network. Two large cortical fields exhibited consistent activation in each contrast: the anterior part of the inferior lateral prefrontal cortex (PFC) and the posterior part of the superior temporal cortex (STP). Intriguingly, these areas were deactivated by gamma-methyl-ionone and methyl-thio-butanoate. These brain regions can be identified as cortical fields underlying other than olfactory functions, including various aspects of social cognition and attention. |
| Doi | 10.1016/j.neuint.2003.10.003 |
| Pmid | 15016474 |
| Wosid | WOS:000220388000004 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |