Morphometric analysis of the primate nasal cavity
Gross, EA; Starr, TB; Randall, HW; Morgan, KT
HERO ID
625447
Reference Type
Journal Article
Subtype
Abstract
Year
1987
Language
English
| HERO ID | 625447 |
|---|---|
| Material Type | Abstract |
| In Press | No |
| Year | 1987 |
| Title | Morphometric analysis of the primate nasal cavity |
| Authors | Gross, EA; Starr, TB; Randall, HW; Morgan, KT |
| Journal | Toxicologist |
| Volume | 7 |
| Issue | 1 |
| Page Numbers | 193 |
| Abstract | The nasal mucosa protects the delicate lower respiratory tract by warming, moistening and cleaning inspired air. The nose also contains the receptors for olfaction and is an important target site for inhaled toxic materials. For use in future dosimetry studies of inhaled gases, morphometric analysis of the primate nasal cavity has been undertaken to determine total nasal cavity surface area and volume of the Rhesus monkey and to quantify the surface areas of squamous, respiratory and olfactory epithelia. Measurements were made on 20, 4μ thick, plastic, step cross-sections (3.89 mm apart) through the nasal cavity and naso-pharynx of an adult male Rhesus monkey. Surface area and airway volume measurements of the nasal passage and maxillary sinus were determined using a Videoplan image analyzer. Data points were collected every .05 mm around the perimeter of each section. The nasal cavity surface area was 81.97 cm2 and the volume was 8.25 cm3. The surface area and volume of the maxillary sinus were 10.67 cm2 and 1.92 cm3 respectively. The information provided by this study, once coupled with data from more animals, will provide useful baseline values for ongoing regional dosimetry studies of inhaled formaldehyde in monkeys. |
| Url | https://www.toxicology.org/pubs/docs/Tox/1987Tox.pdf |
| Is Certified Translation | No |
| Dupe Override | No |
| Conference Location | Washington, DC |
| Conference Name | 26th Annual Meeting of the Society of Toxicology |
| Conference Date | February 23-27, 1987 |
| Is Public | Yes |
| Language Text | English |