More than tenfold increase of arsenic in serum and packed cells of chronic hemodialysis patients
De Kimpe, J; Cornelis, R; Mees, L; Van Lierde, S; Vanholder, R
HERO ID
626998
Reference Type
Journal Article
Year
1993
Language
English
PMID
| HERO ID | 626998 |
|---|---|
| In Press | No |
| Year | 1993 |
| Title | More than tenfold increase of arsenic in serum and packed cells of chronic hemodialysis patients |
| Authors | De Kimpe, J; Cornelis, R; Mees, L; Van Lierde, S; Vanholder, R |
| Journal | American Journal of Nephrology |
| Volume | 13 |
| Issue | 6 |
| Page Numbers | 429-434 |
| Abstract | Arsenic concentrations were determined in serum and packed cells of 7 chronic hemodialysis patients, in fresh dialysate and in a heparin solution. The analytical technique was radiochemical neutron activation analysis. The accuracy of the method was tested by the analysis of As in certified reference materials. Patients showed elevated serum and packed cell arsenic concentrations compared with controls (serum, range: 2.3-79.8 ng As/ml, median: 11.5 ng As/ml; versus range: 0.132-4.783 ng As/ml, median: 0.38 ng As/ml; packed cells, range: 2.1-68.4 ng As/g, median: 9.5 ng As/g; versus range: 0.51-14.44 ng As/g, median: 3.17 ng As/g). Arsenic concentrations remained unaltered, before versus after a single hemodialysis treatment. The arsenic contents of serum and packed cells were significantly correlated (n = 7, r = 0.96, p < 0.05). No arsenic could be detected in the heparin solution or in the dialysate. |
| Doi | 10.1159/000168658 |
| Pmid | 8141175 |
| Wosid | WOS:A1993MV20700001 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | |WOS:A1993MV20700001 |
| Is Public | Yes |
| Language Text | English |
| Keyword | ARSENIC; CHRONIC RENAL FAILURE; CHRONIC HEMODIALYSIS; SERUM; PACKED CELLS; RADIOCHEMICAL NEUTRON ACTIVATION ANALYSIS |
| Is Qa | No |