Oral C-4 plastic explosive in humans - A case series

Davies, JOJ; Roberts, DM; Hittarage, A; Buckley, NA

HERO ID

627787

Reference Type

Journal Article

Year

2007

Language

English

PMID

17503243

HERO ID 627787
In Press No
Year 2007
Title Oral C-4 plastic explosive in humans - A case series
Authors Davies, JOJ; Roberts, DM; Hittarage, A; Buckley, NA
Journal Clinical Toxicology
Volume 45
Issue 5
Page Numbers 454-457
Abstract INTRODUCTION: C-4 is a plastic explosive widely used for demolition in both military and civilian settings. Severe toxicity following unintentional oral exposures or abuse have been reported in single case reports and small case series. CASE SERIES: Seventeen previously healthy male Army commandos admitted to a secondary referral hospital in Sri Lanka following oral C-4 poisoning. METHODS: This data was collected as part of a prospective cohort study recruiting all patients admitted to general hospitals in Sri Lanka with a history of poisoning. History, clinical, and laboratory outcomes were recorded until discharge. RESULTS: All 17 patients survived. The prominent clinical features were seizures, headache, nausea, and vomiting. Hypokalaemia and elevation of creatine kinase, lactate dehydrogenase, and phosphate were noted in all but two patients. Metabolic acidosis occurred in two patients following seizures and this resolved spontaneously. CONCLUSIONS: Management recommendations include standard resuscitation, supportive care, and benzodiazepines for the control of seizures or agitation. Poisoning with C-4 is an unusual cause of seizures which should be considered in patients with access to this agent.
Doi 10.1080/15563650601118044
Pmid 17503243
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword C-4; Explosive; RDX; Abuse; Seizures; Convulsions; Poisoning; Oral
Is Qa No