Mammalian toxicological evaluation of RDX
Cholakis, JM; Wong, LCK; Van Goethem, DL; Minor, J; Short, R; Sprinz, H; Ellis, HV, III
HERO ID
630078
Reference Type
Technical Report
Year
1980
Language
English
| HERO ID | 630078 |
|---|---|
| Year | 1980 |
| Title | Mammalian toxicological evaluation of RDX |
| Authors | Cholakis, JM; Wong, LCK; Van Goethem, DL; Minor, J; Short, R; Sprinz, H; Ellis, HV, III |
| Publisher Text | Midwest Research Institute |
| City | Kansas City, MO |
| Abstract | Acute oral LD50's and standard errors were 119.0 +/- 4.6, 118.7 +/- 4.5, and 118.1 +/- 2.8 mg/kg in male, female and combined sexes of rats. The corresponding mouse LD50's were 97.2 +/- 8.7, 58.9 +/- 26.8, and 80.3 +/- 9.6 mg/kg, respectively. There were no statistically significant sex differences in either species. Toxic signs, including gasping, labored breathing and convulsions, indicated neurotoxicity. |
| Report Number | DAMD17-78-C-8027 |
| Url | http://www.dtic.mil/dtic/tr/fulltext/u2/a092531.pdf |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |