The neurotoxicity of cyclotrimethylenetrinitramine (RDX) in a child: A clinical and pharmacokinetic evaluation

Woody, RC; Kearns, GL; Brewster, MA; Turley, CP; Sharp, GB; Lake, RS

HERO ID

630144

Reference Type

Journal Article

Year

1986

Language

English

PMID

3746987

HERO ID 630144
In Press No
Year 1986
Title The neurotoxicity of cyclotrimethylenetrinitramine (RDX) in a child: A clinical and pharmacokinetic evaluation
Authors Woody, RC; Kearns, GL; Brewster, MA; Turley, CP; Sharp, GB; Lake, RS
Journal Clinical Toxicology
Volume 24
Issue 4
Page Numbers 305-319
Abstract Cyclotrimethylenetrinitramine (RDX) is a highly explosive compound frequently used for both military and civilian purposes. Previously reported cases of human RDX intoxication were limited to wartime settings and have described no human pharmacokinetic data. We report the first human intoxication to occur in a non-wartime setting. This intoxication presented with status epilepticus in a child and permitted the description of RDX human pharmacokinetics. It also suggested a strong association between central nervous system dysfunction and RDX intoxication.
Doi 10.3109/15563658608992595
Pmid 3746987
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Is Qa No