Association of ambient fine particles with out-of-hospital cardiac arrests in New York City

Silverman, RA; Ito, K; Freese, J; Kaufman, BJ; De Claro, D; Braun, J; Prezant, DJ

HERO ID

647265

Reference Type

Journal Article

Year

2010

Language

English

PMID

20729350

HERO ID 647265
In Press No
Year 2010
Title Association of ambient fine particles with out-of-hospital cardiac arrests in New York City
Authors Silverman, RA; Ito, K; Freese, J; Kaufman, BJ; De Claro, D; Braun, J; Prezant, DJ
Journal American Journal of Epidemiology
Volume 172
Issue 8
Page Numbers 917-923
Abstract Cardiovascular morbidity has been associated with particulate matter (PM) air pollution, although the relation between pollutants and sudden death from cardiac arrest has not been established. This study examined associations between out-of-hospital cardiac arrests and fine PM (of aerodynamic diameter < /=2.5 mum, or PM(2.5)), ozone, nitrogen dioxide, sulfur dioxide, and carbon monoxide in New York City. The authors analyzed 8,216 out-of-hospital cardiac arrests of primary cardiac etiology during the years 2002-2006. Time-series and case-crossover analyses were conducted, controlling for season, day-of-week, same-day, and delayed/apparent temperature. An increased risk of cardiac arrest in time-series (relative risk (RR) = 1.06, 95% confidence interval (CI): 1.02, 1.10) and case-crossover (RR = 1.04, 95% CI: 0.99, 1.08) analysis for a PM(2.5) increase of 10 mug/m(3) in the average of 0- and 1-day lags was found. The association was significant in the warm season (RR = 1.09, 95% CI: 1.03, 1.15) but not the cold season (RR = 1.01, 95% CI: 0.95, 1.07). Associations of cardiac arrest with other pollutants were weaker. These findings, consistent with studies implicating acute cardiovascular effects of PM, support a link between PM(2.5) and out-of-hospital cardiac arrests. Since few individuals survive an arrest, air pollution control may help prevent future cardiovascular mortality.
Doi 10.1093/aje/kwq217
Pmid 20729350
Wosid WOS:000283089700006
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science WOS:000283089700006
Is Public Yes
Language Text English
Keyword air pollution; death, sudden, cardiac; emergency medical services; particulate matter
Is Peer Review Yes
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