Refining the aggregate exposure pathway

Tan, YM; Leonard, JA; Edwards, S; Teeguarden, J; Egeghy, P

HERO ID

6571265

Reference Type

Journal Article

Year

2018

Language

English

PMID

29465734

HERO ID 6571265
In Press No
Year 2018
Title Refining the aggregate exposure pathway
Authors Tan, YM; Leonard, JA; Edwards, S; Teeguarden, J; Egeghy, P
Journal Environmental Science: Processes & Impacts
Volume 20
Issue 3
Page Numbers 428-436
Abstract Advancements in measurement technologies and modeling capabilities continue to result in an abundance of exposure information, adding to that currently in existence. However, fragmentation within the exposure science community acts as an obstacle for realizing the vision set forth in the National Research Council's report on Exposure Science in the 21st century to consider exposures from source to dose, on multiple levels of integration, and to multiple stressors. The concept of an Aggregate Exposure Pathway (AEP) was proposed as a framework for organizing and integrating diverse exposure information that exists across numerous repositories and among multiple scientific fields. A workshop held in May 2016 followed introduction of the AEP concept, allowing members of the exposure science community to provide extensive evaluation and feedback regarding the framework's structure, key components, and applications. The current work briefly introduces topics discussed at the workshop and attempts to address key challenges involved in refining this framework. The resulting evolution in the AEP framework's features allows for facilitating acquisition, integration, organization, and transparent application and communication of exposure knowledge in a manner that is independent of its ultimate use, thereby enabling reuse of such information in many applications.
Doi 10.1039/c8em00018b
Pmid 29465734
Wosid WOS:000428988500001
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English