Measurement of volatile organic compounds in human blood

Ashley, DL; Bonin, MA; Cardinali, FL; Mccraw, JM; Wooten, JV

HERO ID

658651

Reference Type

Journal Article

Subtype

Review

Year

1996

Language

English

PMID

8933028

HERO ID 658651
Material Type Review
In Press No
Year 1996
Title Measurement of volatile organic compounds in human blood
Authors Ashley, DL; Bonin, MA; Cardinali, FL; Mccraw, JM; Wooten, JV
Journal Environmental Health Perspectives
Volume 104
Issue Suppl 5
Page Numbers 871-877
Abstract Volatile organic compounds (VOCs) are an important public health problem throughout the developed world. Many important questions remain to be addressed in assessing exposure to these compounds. Because they are ubiquitous and highly volatile, special techniques must be applied in the analytical determination of VOCs. The analytical methodology chosen to measure toxicants in biological materials must be well validated and carefully carried out; poor quality assurance can lead to invalid results that can have a direct bearing on treating exposed persons. The pharmacokinetics of VOCs show that most of the internal dose of these compounds is quickly eliminated, but there is a fraction that is only slowly removed, and these compounds may bioaccumulate. VOCs are found in the general population at the high parts-per-trillion range, but some people with much higher levels have apparently been exposed to VOC sources away from the workplace. Smoking is the most significant confo
Doi 10.2307/3433004
Pmid 8933028
Wosid WOS:A1996VU00500004
Is Certified Translation No
Dupe Override No
Comments Clin. Chem. (Washington, DC) 40: 1401-1404.
Is Public Yes
Language Text English
Keyword BIOCHEMISTRY; BLOOD CHEMICAL ANALYSIS; BODY FLUIDS/CHEMISTRY; LYMPH/CHEMISTRY; POISONING; ANIMALS, LABORATORY; HOMINIDAE; Biochemical Studies-General; Toxicology-General; 1634-04-4; 127-18-4; 108-88-3; 108-38-3; 106-46-7; 106-42-3; 100-42-5; 100-41-4; 95-47-6; 75-25-2; 75-09-2; 71-55-6; 71-43-2; 67-66-3; 56-23-5
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