Sister chromatid exchange induction potential of the halogenated hydrocarbons produced during water chlorination

Sobti, RC

HERO ID

677703

Reference Type

Journal Article

Year

1984

HERO ID 677703
In Press No
Year 1984
Title Sister chromatid exchange induction potential of the halogenated hydrocarbons produced during water chlorination
Authors Sobti, RC
Journal Chromosome Information Service
Volume 37
Page Numbers 17-19
Abstract Currently, the possibility of the production of low molecular weight chlorinated hydrocarbons through the use of chlorination for water purification is of great concern. The concern focuses principally on the four trihalmethanes viz., chloroform, bromodichloromethane (BDCM), dibromochloromethane (DBCM) and bromoform. Beside these, the formation of carbon tetrachloride and 1, 2 dichloroethane has also been detected. The halogenated hydrocarbons produced by chlorination seem to result from naturally occurring humic substances as precursors. The maximum concentrations of these materials found were: chloroform, 54 mg/l; BDCM, 20 mg/l; DBCM, 13 mg/l and bromoform, 10 mg/l. Since all these are suspect chemicals, it has been attempted to find out the possible mutagenic potential of chloroform, BDCM and DBCM by subjecting them to SCE assay.
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Keyword GENETICS; CYTOGENETICS; ANIMALS/GENETICS; GENETICS,MEDICAL; BIOCHEMISTRY; POISONING; ANIMALS,LABORATORY; ENVIRONMENTAL POLLUTANTS/POISONING; OCCUPATIONAL DISEASES; CULTURE MEDIA; TISSUE CULTURE; SANITATION; SEWAGE; Genetics and Cytogenetics-General; Genetics and Cytogenetics-Animal; Genetics and Cytogenetics-Human; Biochemical Studies-General; Toxicology-General; Toxicology-Environmental and Industrial Toxicology; Public Health: Environmental Health-Sewage Disposal and Sanitary Measures; Public Health: Environmental Health-Air; 7782-50-5; 124-48-1; 75-27-4; 75-25-2; 67-66-3
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