Gas chromatography-mass spectrometry determination of the migration of phthalate plasticisers from polyvinyl chloride toys and childcare articles
Earls, AO; Axford, IP; Braybrook, JH
HERO ID
679460
Reference Type
Journal Article
Year
2003
Language
English
PMID
| HERO ID | 679460 |
|---|---|
| In Press | No |
| Year | 2003 |
| Title | Gas chromatography-mass spectrometry determination of the migration of phthalate plasticisers from polyvinyl chloride toys and childcare articles |
| Authors | Earls, AO; Axford, IP; Braybrook, JH |
| Journal | Journal of Chromatography A |
| Volume | 983 |
| Issue | 1-2 |
| Page Numbers | 237-246 |
| Abstract | Two laboratory-based linear horizontal agitation methods for determining a range of phthalate esters from soft polyvinyl chloride (PVC) toys are presented in compliance with EU legislation. Both of these methods were validated through interlaboratory trials using a PVC reference disc and four soft PVC toy/childcare articles intended or likely to be mouthed. Two of these commercial samples contained diisononyl phthalate (DINP), one diisodecyl phthalate (DIDP) and one bis(2-ethylhexyl) phthalate (DEHP). Acceptable repeatability (r, within-laboratory) and reproducibility (R, between-laboratory) data were demonstrated for both the analytical detection technique (GC-MS) (r = 9.8% and R = 8.1%) and agitation/extraction procedure (r=21.9% and R = 35.3% at 37 degrees C; r = 22.7% and R = 31.1% at 65 degrees C) for DINP. This was achieved through the participation of six laboratories. The remaining three phthalates from the EU Scientific Committee for Toxicity, Ecotoxicity and the Environment (CSTEE) list--dibutyl phthalate (DBP), benzyl butyl phthalate (BBP) and di-n-octyl phthalate (DnOP)--were not tested due to the unavailability of suitable materials. |
| Doi | 10.1016/S0021-9673(02)01736-3 |
| Pmid | 12568386 |
| Wosid | WOS:000180309500021 |
| Url | https://search.proquest.com/docview/73004420?accountid=171501 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | analysis; chemistry; Esters; Gas Chromatography-Mass Spectrometry; methods; Phthalic Acids; Plasticizers; Play and Playthings; Polyvinyl Chloride; Reproducibility of Results; Safety; Sensitivity and Specificity; Tobacco; toxicity |
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