Inspiratory deposition of ultrafine particles in human nasal replicate cast
Swift, DL; Montassier, N; Hopke, PK; Karpen-Hayes, K; Cheng, YS; Su, YF; Yeh, HC; Strong, JC
| HERO ID | 6956 |
|---|---|
| In Press | No |
| Year | 1992 |
| Title | Inspiratory deposition of ultrafine particles in human nasal replicate cast |
| Authors | Swift, DL; Montassier, N; Hopke, PK; Karpen-Hayes, K; Cheng, YS; Su, YF; Yeh, HC; Strong, JC |
| Journal | Journal of Aerosol Science |
| Volume | 23 |
| Page Numbers | 65-72 |
| Abstract | The deposition of particles in replicate cast models of the human nasal cavity has been measured in three different laboratories for a range of particle sizes from 0.6 to 200 nm. The results of these measurements on four different casts can be fit by a single equation of the form eta = 1 -exp [-bQ-1/8 D1/2], where eta is the fraction of particles deposited in the nasal cavity, Q is the volumetric flow rate (1 min-1), D is the particle diffusion coefficient (cm2s-1), and b is found to be 12.65 +/- 0.17. The measurements were conducted over a range of flow rates from 1.4 to 28.7 1 min-1 (50 1 min-1 for sizes from 4.6 to 200 nm) using radon and thoron decay product aerosols as well as larger ultrafine particles. These results thus represent a current best estimate of the diffusional deposition of ultrafine particles in the human nasal cavity. |
| Doi | 10.1016/0021-8502(92)90318-P |
| Wosid | WOS:A1992HM69500006 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |