PPARs: diverse regulators in energy metabolism and metabolic diseases
Wang, Y
HERO ID
699505
Reference Type
Journal Article
Subtype
Review
Year
2010
Language
English
PMID
| HERO ID | 699505 |
|---|---|
| Material Type | Review |
| In Press | No |
| Year | 2010 |
| Title | PPARs: diverse regulators in energy metabolism and metabolic diseases |
| Authors | Wang, Y |
| Journal | Cell Research |
| Volume | 20 |
| Issue | 2 |
| Page Numbers | 124-137 |
| Abstract | The nuclear receptor PPARs are fundamentally important for energy homeostasis. Through their distinct yet overlapping functions and tissue distribution, the PPARs regulate many aspects of energy metabolism at the transcriptional level. Functional impairment or dysregulation of these receptors leads to a variety of metabolic diseases, while their ligands offer many metabolic benefits. Studies of these receptors have advanced our knowledge of the transcriptional basis of energy metabolism and helped us understand the pathogenic mechanisms of metabolic syndrome. |
| Doi | 10.1038/cr.2010.13 |
| Pmid | 20101262 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Is Qa | No |