Antibacterial and Antioxidant potential of White and Pink Nelumbo Nucifera Gaertn Flowers
Venkatesh, B; Dorai, A; ,
| HERO ID | 7075608 |
|---|---|
| In Press | No |
| Year | 2011 |
| Title | Antibacterial and Antioxidant potential of White and Pink Nelumbo Nucifera Gaertn Flowers |
| Authors | Venkatesh, B; Dorai, A; , |
| Page Numbers | 213-217 |
| Abstract | The recent interest on alternative medicine has taken up great dimensions in changing the health care scenario across the globe. The worldwide interest in medicinal plants reflects recognition of the validity of studying the antimicrobial and antioxidant activity. Hence the present study was carried out to explore antibacterial and antioxidant potential of hydroethanolic extract of both white and pink flowers of Nelumbo nucifera Gaertn (Nelumbonaceae) flower in vitro. The antibacterial activity was screened against different bacterial strains by detecting zone of inhibition and minimum inhibitory concentration (MIC). The zone of inhibition and MIC values were compared with control compared with standard antibiotic disc suggesting their potential as alternatives to orthodox antibiotics in the treatment of infectious caused by these microorganisms. Total antioxidant potential was evaluated in hydroethanolic extract of white Nelumbo nucifera (HEWNN) flower and hydroethanolic extract of pink Nelumbo nucifera (HEPNN) flower by: Ferric reducing antioxidant power (FRAP), Hemoglobin glycosylation,Reducing power and Phosphomolybdenum and compared with the standard ascorbic acid in dose dependent manner. Both HEWNN and HEPNN flower extracts showed maximum activity 16.53 mg and 14.21 mg at 1000 mu g/ml concentration in FRAP assay. Significantly high antioxidant activity (55.5% & 41.6%) was noticed in haemoglobin glycosylation followed reducing power (0.52 & 0.45 Abs). The results suggest that alkaloids, phenols and flavonoids in flowers provide considerable antioxidant activity. However, in comparison with HEPNN flower, HEWNN flower extract exerted effective antibacterial and potent antioxidant activity which can be used as a lead compound for drug development in the future. |
| Wosid | WOS:000392766100046 |
| Is Certified Translation | No |
| Dupe Override | No |
| Conference Location | Singapore, SINGAPORE |
| Conference Name | International Conference on Bioscience, Biochemistry and Bioinformatics (ICBBB 2011) |
| Is Public | Yes |