Transplacental transfer of asbestos in pregnant mice

Haque, AK; Vrazel, DM

HERO ID

709615

Reference Type

Journal Article

Year

1998

Language

English

PMID

9557202

HERO ID 709615
In Press No
Year 1998
Title Transplacental transfer of asbestos in pregnant mice
Authors Haque, AK; Vrazel, DM
Journal Bulletin of Environmental Contamination and Toxicology
Volume 60
Issue 4
Page Numbers 620-625
Abstract Occupational exposure to asbestos has been on decline in the US over the last 2-3 decades. There is, however, concern that environmental asbestos exposure is increasing through the use of asbestos-containing products (Churg 1988; Edelman 1988; Jarvholm et al. 1988; Sebastein et al. 1989). Most of the previous studies on asbestos exposure have included adult subjects only. However, recent studies have demonstrated asbestos fibers in the tissues and/or placenta digests of a series of autopsied stillborn infants (Haque et al. 1992; 1995; 1996). One of these studies found a highly significant difference (p = 0.001) between the mean asbestos counts of tissues from 92 autopsied stillborn infants (52,894 fibers/g) and 45 control placentas of healthy liveborn infants (19 fibers/g) (Haque et al. 1996). A possible relationship between stillbirths and asbestos fiber presence was also suggested by this study. Additionally, significant association was found between a maternal history of previous abortions and asbestos fiber presence in the stillborn tissues (p = 0.007) (Haque et al. 1996).
Doi 10.1007/s001289900671
Pmid 9557202
Wosid WOS:000072812300018
Is Certified Translation No
Dupe Override No
Comments Journal: ISSN:
Is Public Yes
Language Text English
Keyword Environment Abstracts; MINERAL FIBERS; REPRODUCTION, ANIMAL; ASBESTOS; ENA 07:General
Is Qa No