Alpha 2-urinary globulin-associated nephropathy as a mechanism of renal tubule cell carcinogenesis in male rats
Swenberg, JA; Lehman-Mckeeman, LD
HERO ID
732735
Reference Type
Book/Book Chapter
Subtype
Review
Year
1999
Language
English
PMID
| HERO ID | 732735 |
|---|---|
| Material Type | Review |
| Year | 1999 |
| Title | Alpha 2-urinary globulin-associated nephropathy as a mechanism of renal tubule cell carcinogenesis in male rats |
| Book Title | Species Differences in Thyroid, Kidney, and Urinary Bladder Carcinogenesis |
| Authors | Swenberg, JA; Lehman-Mckeeman, LD |
| Editor | C. C. Capen; E. Dybing; J. M. Rice; J. D. Wilbourn |
| Publisher Text | International Agency for Research on Cancer |
| City | Lyon, France |
| Volume | 147 |
| Page Numbers | 95-118 |
| Abstract | This publication originates from a workshop held in 1997 to consider how rodent tumours of urinary bladder, renal cortex, and thyroid gland should be treated within the IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. The workshop also addressed the predictive value of these tumours for the identification of carcinogenic hazards to humans when they occur alone and when they occur along with tumours in other organs. In the following sections, etiological risk factors in humans and experimental animals as well as the hypotheses underlying the proposed species-specific mechanisms for each of the above-mentioned tumour types are summarized. Finally, for each tumour type, recommendations are presented on how the mechanistic data could be used in the overall evaluation of carcinogenicity to humans. |
| Pmid | 10457913 |
| Url | http://apps.who.int/bookorders/anglais/detart1.jsp?sesslan=1&codlan=1&codcol=73&codcch=147 |
| Is Certified Translation | No |
| Dupe Override | No |
| Series | IARC Scientific Publications |
| Isbn | 9789283221470 |
| Is Public | Yes |
| Language Text | English |
| Relationship(s) |
|