n-Octanol/water partition co-efficient (Kow) for ethyl tertiary butyl ether (ETBE) at 25 degrees C +/- 1 degree C
Montgomery, CR
| HERO ID | 77029 |
|---|---|
| Year | 1994 |
| Title | n-Octanol/water partition co-efficient (Kow) for ethyl tertiary butyl ether (ETBE) at 25 degrees C +/- 1 degree C |
| Authors | Montgomery, CR |
| Abstract | The objective of this study was to evaluate the n-octanol/water partitioning coefficient (Kow) for ethyl tertiary butyl ether (ETBE). The purpose of this report is to summarize the data from two determinations of Kow when both concentrations of the analyte are below the limit of solubility, and differ by a factor of 10. The test substance, ETBE, was partitioned between n-octanol saturated MilIiQ purified water and MilliQ purified water saturated n-octanol at two concentrations (1 x 10-2 and 1 x l0-3M). One time zero sampling point, and two post equilibrium sampling points were used to determine partitioning. Aliquots were taken from each of the aqueous and organic phases, from each sample, and analyzed for ETBE using gas chromatography with FID detection. Equilibrium time was determined from a non-GLP prestudy screen to be <0.5 hours. The results of the study indicate that the analytical method was sensitive enough to detect the concentration of the analyte in both the water and n-octanol phases at both concentrations used. The study shows that the ETBE preferentially partitions to the n-octanol phase, and the average values for Kow and log (Kow) at 25░C +/- 1░C are as follows: High Concentration (1 x 10-2M): Kow = 28.3 log(Kow) = 1.45 Low Concentration (1 x 10-3M): Kow = 31.4 log(Kow) = 1.50 Average of all Kow values for Both Concentrations: Kow = 30.1 ± 3.02 SD log(Kow) = 1.48 ± 0.0434 SD |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | ECRIB. Make subscript and italicize ow in (Kow); use symbol for degree(s).Cambridge, MA: BIODEVELOPMENT Laboratories, Inc.; study no. 57374-2; January 19. |
| Is Public | Yes |
| Is Qa | No |