Genetic toxicology salmonella/microsomal assay on hexabromocyclododecane with cover letter dated 030890

HERO ID

787661

Reference Type

Technical Report

Subtype

TSCA Submission

Year

1990

Language

English

HERO ID 787661
Material Type TSCA Submission
Year 1990
Title Genetic toxicology salmonella/microsomal assay on hexabromocyclododecane with cover letter dated 030890
Authoring Organization Ethyl Corporation
Publisher Text Ethyl Corporation
City Baton Rouge, LA
Abstract Hexabromocyclododecane was evaluated for mutagenicity by plate assay in the bacterium, Salmonella typhimurium, strains TA1535, TA1537, TA98, and TA100, both in the presence and absence of Aroclor 1254-induced rat liver homogenate. Positive (substance not identified), solvent (acetone), and untreated controls were utilized. Test concentrations ranged from 0.05 to 5.0 mg/plate. The high dose did not produce toxicity in any strain. A dose-related increase was observed in the number of revertant colonies in strains TA100 and TA1535 both in the presence and absence of metabolic activation.
Report Number TSCATS/405818. OTS0522235. Doc I.D. 86900000164
Ntis Number OTS0522235
Tscats Number TSCATS/405818
Url https://ntrl.ntis.gov/NTRL/dashboard/searchResults.xhtml?searchQuery=OTS0522235
Is Certified Translation No
Dupe Override No
Comments Journal: EPA ISSN:
Is Public Yes
Language Text English
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