Temporal trends of polybrominated diphenyl ethers and hexabromocyclododecane in milk from Stockholm mothers, 1980-2004

Fängström, B; Athanassiadis, I; Odsjö, T; Norén, K; Bergman, A

HERO ID

787664

Reference Type

Journal Article

Year

2008

Language

English

PMID

18186105

HERO ID 787664
In Press No
Year 2008
Title Temporal trends of polybrominated diphenyl ethers and hexabromocyclododecane in milk from Stockholm mothers, 1980-2004
Authors Fängström, B; Athanassiadis, I; Odsjö, T; Norén, K; Bergman, A
Journal Molecular Nutrition and Food Research
Volume 52
Issue 2
Page Numbers 187-193
Abstract Environmental and human exposures to brominated flame retardants (BFR) have been of emerging concern since some BFR are persistent and bioaccumulative compounds. Among those, polybrominated diphenyl ethers (PBDE) have frequently been reported in low to high ng/g concentrations in human blood around the world while hexabromocyclododecane (HBCDD) only occasionally has been reported and then in the low ppb concentrations in human blood. The present study concerns PBDE congener and HBCDD concentrations in human milk from Stockholm from 1980 to 2004. HBCDD concentrations has increased four to five times since 1980 until 2002 but seems to have stabilized at this concentration in the last years (2003/04). Similarly, BDE-153 has continued to increase at least to 2001, after which it has stabilized in the mother's milk. Other PBDE congeners with four to five bromine substituents peaked 5 years earlier (1995) and are all decreasing. DecaBDE (BDE-209) is not a suitable biomarker for time trend studies according to the present results, showing no changes over time. This is likely due to its short apparent half-life in humans and poor transfer from blood to milk.
Doi 10.1002/mnfr.200700182
Pmid 18186105
Wosid WOS:000253440300002
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword exposure; human milk; level; hexabromocyclododecane; polybrominated diphenyl ethers
Is Qa No