Effect of short-term exposure to low levels of gaseous pollutants on chronic obstructive pulmonary disease hospitalizations

Yang, Q; Chen, Y; Krewski, D; Burnett, RT; Shi, Y; McGrail, KM

HERO ID

90184

Reference Type

Journal Article

Year

2005

Language

English

PMID

16053934

HERO ID 90184
In Press No
Year 2005
Title Effect of short-term exposure to low levels of gaseous pollutants on chronic obstructive pulmonary disease hospitalizations
Authors Yang, Q; Chen, Y; Krewski, D; Burnett, RT; Shi, Y; McGrail, KM
Journal Environmental Research
Volume 99
Issue 1
Page Numbers 99-105
Abstract We examined the associations between gaseous pollutants and hospitalization for chronic obstructive pulmonary diseases (COPD) among elderly people living in Vancouver, British Columbia, Canada, a city in which ambient air pollution levels are relatively low. We regressed the logarithm of daily counts of acute COPD hospitalization during the 5-year period from 1994 to 1998 on the daily mean levels of each pollutant, after accounting for seasonal and subseasonal fluctuations, non-Poisson dispersion, and weather variables. Nitrogen dioxide and carbon monoxide were significantly associated with hospitalization for COPD, and the magnitude of effects was increased slightly with increasing days of exposure averaging, with the relative risk for a 7-day average being 1.11 (95%CI: 1.04, 1.20) and 1.08 (1.02, 1.13) for nitrogen dioxide and carbon monoxide, respectively. There was no significant association between either sulfur dioxide or ozone and COPD hospitalization. The combined relative risk for all four gaseous pollutants on COPD hospitalization was 1.21. The effects of gaseous pollutants on COPD hospitalization were not significant after adjustment for PM10, although its inclusion did not have a marked effect on the point estimates for relative risks. Nitrogen dioxide has a significant impact on COPD hospitalization. Further studies are needed to separate the effects of single pollutants from the combined effects of the complex mixture of air pollutants in urban atmospheres.
Doi 10.1016/j.envres.2004.09.014
Pmid 16053934
Wosid WOS:000231197400013
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science WOS:000231197400013
Is Public Yes
Language Text English
Keyword COPD; hospitalization; gaseous pollutants; particulate; relative risk