Salmonella mutagenicity tests: V. Results from the testing of 311 chemicals
Zeiger, E; Anderson, B; Haworth, S; Lawlor, T; Mortelmans, K
HERO ID
95748
Reference Type
Journal Article
Year
1992
Language
English
PMID
| HERO ID | 95748 |
|---|---|
| In Press | No |
| Year | 1992 |
| Title | Salmonella mutagenicity tests: V. Results from the testing of 311 chemicals |
| Authors | Zeiger, E; Anderson, B; Haworth, S; Lawlor, T; Mortelmans, K |
| Journal | Environmental and Molecular Mutagenesis |
| Volume | 19 |
| Issue | Suppl. S21 |
| Page Numbers | 2-141 |
| Abstract | #311 chemicals were tested under code, for mutagenicity, in Salmonella typhimurium; 35 of the chemicals were tested more than once in the same or different laboratories. The tests were conducted using a preincubation protocol in the absence of exogenous metabolic activation, and in the presence of liver S-9 from Aroclor-induced male Sprague-Dawley rats and Syrian hamsters. Some of the volatile chemicals were also tested in desiccators. A total of 120 chemicals were mutagenic or weakly mutagenic, 3 were judged questionable, and 172 were non-mutagenic. The remaining 16 chemicals produced different responses in the two or three laboratories in which they were tested. The results and data from these tests are presented. |
| Doi | 10.1002/em.2850190603 |
| Pmid | 1541260 |
| Wosid | WOS:A1992HK48300001 |
| Url | https://onlinelibrary.wiley.com/doi/10.1002/em.2850190603 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Source: Web of Science WOS:A1992HK48300001 |
| Is Public | Yes |
| Language Text | English |
| Keyword | Ames test; National Toxicology Program; mutagenicity testing; Salmonella |
| Relationship(s) |
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