Sodium orthovanadate and cardiac activity in teleost fish
Sargent, JR; Bell, MV; Kelly, KF; Johnstone, A; Hawkins, A; Hall, CD
HERO ID
9674780
Reference Type
Journal Article
Year
1980
Language
English
| HERO ID | 9674780 |
|---|---|
| In Press | No |
| Year | 1980 |
| Title | Sodium orthovanadate and cardiac activity in teleost fish |
| Authors | Sargent, JR; Bell, MV; Kelly, KF; Johnstone, A; Hawkins, A; Hall, CD |
| Journal | Comparative Biochemistry and Physiology - Part C: Comparative Pharmacology |
| Volume | 66 |
| Issue | 1 |
| Page Numbers | 111-114 |
| Abstract | 1. The electrocardiogram was monitored in decerebrate cod and trout after intravenous injection of sodium orthovanadate. 2. Slowing of the heart rate occurred 1 min after injecting 84 μg of Na3VO4 (equivalent to 23 μg elemental V). 3. Heart beat was apparently suppressed for up to 30 min after injecting 168 μg of Na3VO4 and then returned to normal. 4. Significant changes in heart rate and gill ventilation rate did not occur in fish exposed to 10−4 M orthovanadate in the external medium for up to 6 days. 5. Results are discussed in terms of the possible toxicity of environmental vanadium to aquatic species. |
| Doi | 10.1016/0306-4492(80)90081-7 |
| Wosid | WOS:A1980JV20000016 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |