Effect of dietary calcium glucarate on skin tumorigenesis in sencar mice
Dwivedi, C; Zeigler, SD; Webb, TE
HERO ID
2126383
Reference Type
Journal Article
Year
1991
Language
English
| HERO ID | 2126383 |
|---|---|
| In Press | No |
| Year | 1991 |
| Title | Effect of dietary calcium glucarate on skin tumorigenesis in sencar mice |
| Authors | Dwivedi, C; Zeigler, SD; Webb, TE |
| Journal | Biochemical Archives |
| Volume | 7 |
| Issue | 4 |
| Page Numbers | 293-296 |
| Abstract | Effect of Dietary Calcium Glucarate (CaGT) on 7,12-dimethylbenz(a)anthracene (DMBA)-induced and 12-0-tetradecanoylphorbol-13-acetate (TPA)-promoted skin papillomas formation was evaluated in SENCAR mice. CaGT (4%)-supplemented diet did not produce any significant effect on the papilloma formation contrary to the results observed in CD-1 mice. Calcium gluconate (CaGL), used as a calcium control also exhibited effects similar to the CaGT. Thus, the amount of calcium present in the diet appears to be modifying factors in the skin papilloma formation in the skin tumor sensitive SENCAR mice. The calcium dependent TPA promotion may be related to the genetic predisposition of various calcium modifying factors in the different stocks and strains of mice. |
| Wosid | WOS:A1991GW96200005 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |