Mutagenicity of diisopropylamine dichloroacetate, the "active constituent" of vitamin B15 (pangamic acid)
Gelernt, MD; Herbert, V
HERO ID
2207460
Reference Type
Journal Article
Year
1982
Language
English
PMID
| HERO ID | 2207460 |
|---|---|
| In Press | No |
| Year | 1982 |
| Title | Mutagenicity of diisopropylamine dichloroacetate, the "active constituent" of vitamin B15 (pangamic acid) |
| Authors | Gelernt, MD; Herbert, V |
| Journal | Nutrition and Cancer |
| Volume | 3 |
| Issue | 3 |
| Page Numbers | 129-133 |
| Abstract | Diisopropylamine dichloroacetate, the active component of many formulations of pangamic acid (trade-named "vitamin B15"), and diisopropylamine, a component of diisopropylamine dichloroacetate, both demonstrate mutagenicity in the Ames Salmonella/mammalian microsome mutagenicity test. Ninety percent of such agents prove carcinogenic, and this long-term possibility must be considered in any proposed use of pangamic acid containing diisopropylamine or diisopropylamine dichloroacetate. |
| Doi | 10.1080/01635588109513714 |
| Pmid | 6752894 |
| Wosid | BCI:BCI198375035154 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Note: PubMed, WoS, and Toxline all say 1982. Only Taylor & Francis says volume 3 is from 1981. Assume (for now) the publisher later did some renumbering. The PubMed, WoS, and Toxline references were added closer to the time of publication and probably more accurately reflect the true publication information. |
| Is Public | Yes |
| Language Text | English |
| Relationship(s) |
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