Distinction between the common symptoms of the phosphate-depletion syndrome and glucocorticoid-induced disease

Goodman, M; Solomons, CC; Miller, PD

HERO ID

4559952

Reference Type

Journal Article

Year

1978

Language

English

PMID

309283

HERO ID 4559952
In Press No
Year 1978
Title Distinction between the common symptoms of the phosphate-depletion syndrome and glucocorticoid-induced disease
Authors Goodman, M; Solomons, CC; Miller, PD
Journal American Journal of Medicine
Volume 65
Issue 5 (November 1978)
Page Numbers 868-872
Abstract A phosphate depletion syndrome developed in a steroid-dependent asthmatic patient. Initially, the clinical picture was confused with steroid-associated myopathy rather than the phosphate depletion syndrome which has similar symptoms. The classic biochemical findings led to the correct diagnosis. Cessation of phosphate-binding antacids and phosphorus repletion rapidly corrected the biochemical findings and led to the patient's clinical improvement. Platelet phosphate metabolism was evaluated; it was found to correlate with the phosphorus-depleted state and clinical recovery with phosphate repletion. Attention is drawn to the clinical entity of phosphate depletion which may mimic steroid-induced side effects, both of which may occur in patients receiving steroids and antacids.
Pmid 309283
Is Certified Translation No
Dupe Override 4559952
Is Public Yes
Language Text English
Keyword Abridged Index Medicus; Index Medicus