A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Hunt, MJ; Barnetson, RS
HERO ID
4946098
Reference Type
Journal Article
Year
1992
Language
English
PMID
| HERO ID | 4946098 |
|---|---|
| In Press | No |
| Year | 1992 |
| Title | A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne |
| Authors | Hunt, MJ; Barnetson, RS |
| Journal | Australasian Journal of Dermatology |
| Volume | 33 |
| Issue | 3 |
| Page Numbers | 131-134 |
| Abstract | Alpha hydroxy acids (AHA's) or "fruit acids" are a special group of organic acids found in many natural foods. They have been described in the literature for the treatment of a number of conditions in which abnormal keratinization consistently contributes to pathogenesis. These include the icthyoses, warts, psoriasis, eczema and acne. We have performed a double-blind clinical trial on 150 patients to evaluate the efficacy and skin tolerance of the alpha hydroxy acid gluconolactone 14% in solution (Nuvoderm lotion) in the treatment of mild to moderate acne when compared with its vehicle (placebo) and 5% benzoyl peroxide lotion. The results of this study showed that both gluconolactone and benzoyl peroxide had a significant effect in improving patients' acne by reducing the number of lesions (inflamed and non-inflamed). Furthermore, fewer side-effects were experienced by patients treated with gluconolactone when compared with benzoyl peroxide. |
| Pmid | 1303072 |
| Is Certified Translation | No |
| Dupe Override | 4946098 |
| Is Public | Yes |
| Language Text | English |