Potassium gluconate and ATP effects on chromosome aberration yield

Beatty, AV; Beatty, JW

HERO ID

4947058

Reference Type

Journal Article

Year

1960

Language

English

PMID

16590775

HERO ID 4947058
In Press No
Year 1960
Title Potassium gluconate and ATP effects on chromosome aberration yield
Authors Beatty, AV; Beatty, JW
Journal Proceedings of the National Academy of Sciences of the United States of America
Volume 46
Issue 11
Page Numbers 1488-1492
Abstract Aberration yields were determined from Tradescantia micro-spores subjected to 400 r of X-radiation and pre- or post-treated in chemical compounds. In material irradiated at 30[degree] C, the control yielded 0.24 aberrations per cell while material treated in ATP gave 0.14, in potassium gluconate 0.13, and in 6-phosphogluconate 0.12. Material simultaneously treated in ATP and gluconate gave 0.10. Material irradiated at 40[degree] C gave 0.66 for the controls, 0.19 for ATP, 0.21 for gluconate, 0.23 for 6-phosphogluconate, and 0.17 for the simultaneous treatment with ATP and gluconate. Material irradiated at 0.2[degree] C gave 0.14 for the control 0.10 for ATP, 0.11 for gluconate, 0.09 for 6-phosphogluconate, and 0.10 for the simultaneous use of ATP and gluconate. The postirradiative treatment with ATP or gluconate indicated that these compounds act on the recovery mechanism of radiation damage. Both the glycolytic and the hexose monophosphate pathways appear capable of releasing energy for repair from radiation damage. || ABSTRACT AUTHORS: Auth. summ
Doi 10.1073/pnas.46.11.1488
Pmid 16590775
Wosid BCI:BCI19613600074712
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English