A case of acebutolol intoxication
Sangster, B; de Wildt, D; van Dijk, A; Klein, S
| HERO ID | 4947636 |
|---|---|
| In Press | No |
| Year | 1983 |
| Title | A case of acebutolol intoxication |
| Authors | Sangster, B; de Wildt, D; van Dijk, A; Klein, S |
| Journal | Journal of Toxicology: Clinical Toxicology |
| Volume | 20 |
| Issue | 1 |
| Page Numbers | 69-77 |
| Abstract | A case of a nonfatal acebutolol intoxication in a 15 year old female is described. Ingestion of 7600 mg acebutolol resulted in a plasma acebutolol concentration of 15 mg/1 one hour after ingestion. The patient remained conscious, had a severe hypotension and the electrocardiogram showed a 1st degree AV-block and severe intraventricular conduction disturbances at a rate of 70 bpm. After the administration of calcium gluconate and plasma the blood pressure gradually increased to normal values in 2 hours time. Plasma halflife of acebutolol was 8 hours. Pathophysiology of acebutolol intoxication is discussed. |
| Pmid | 6887301 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |