The effect of collagen-hydrolysate calcium on prevention of osteoporosis
Han, B; Zhang, G; Du, M; Shi, Y; Li, C; Yue, X; Yang, C
HERO ID
4948855
Reference Type
Book/Book Chapter
Year
2009
Language
English
| HERO ID | 4948855 |
|---|---|
| Year | 2009 |
| Title | The effect of collagen-hydrolysate calcium on prevention of osteoporosis |
| Book Title | Proceedings of 2009 International Conference of Natural Product And Traditional Medicine, Vols 1 and 2 |
| Authors | Han, B; Zhang, G; Du, M; Shi, Y; Li, C; Yue, X; Yang, C |
| Editor | Liu, J; Vittori, S; Yang, C |
| Publisher Text | Scientific & Technical Development Inc |
| City | Flushing, NY |
| Page Numbers | 345-348 |
| Abstract | Collagen hydrolysates from porcine bone were prepared using Papain and Flavourzyme, and the degree of hydrolysis was 17.34%. Subsequently, collagen hydrolysates combined with calcium to develop collagen-hydrolysate calcium, and calcium accounted for 4.65%. Wistar rats were given tretinoin for inducing the osteoporosis to investigate prevention of collagen-hydrolysate calcium. Then rats were randomly divided into five groups involved in control group without treatment, model group, low-dose, high-dose and group treated with Calcium Gluconate. Results shown that collagen-hydrolysate calcium can significantly improved bone mass, calcium content and BMD (P<0.05) of thighbone. In the meantime, feeding collagen-hydrolysate calcium with high dose increased significantly phosphorus content and ALP activity (P < 0.05). Histopathologic analysis with paraffin sections in shinbones of low dose and high dose groups, showing symmetrical shinbone trabeculae. |
| Wosid | WOS:000274286500080 |
| Is Certified Translation | No |
| Dupe Override | No |
| Conference Location | NW Univ, Xian, Peoples Republic of China |
| Isbn | 978-0-982-24412-8 |
| Conference Name | International Conference of National Product and Traditional Medicine |
| Conference Date | October 16-18, 2009 |
| Is Public | Yes |
| Language Text | English |
| Keyword | porcine bone; collagen-hydrolysate calcium; osteoporosis |