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HERO ID
10506902
Reference Type
Journal Article
Title
Naloxone's Pentapeptide Binding Site on Filamin A Blocks Mu Opioid Receptor-Gs Coupling and CREB Activation of Acute Morphine (Retraction of Vol 4, art no E4282, 2009)
Author(s)
Wang, HY; Burns, LH
Year
2022
Is Peer Reviewed?
1
Journal
PLoS ONE
EISSN:
1932-6203
Publisher
Public Library Science
Location
SAN FRANCISCO
Volume
17
Issue
3
Language
English
DOI
10.1371/journal.pone.0266629
Web of Science Id
WOS:000786647900056
Relationship(s)
is retraction of
2596558
Naloxone's pentapeptide binding site on filamin A blocks Mu opioid receptor-Gs coupling and CREB activation of acute morphine
Abstract
A fleet of thirteen in-service global container ships continuously measured the air dose rates over the North Pacific after the Fukushima Daiichi Nuclear Power Station (FDNPS) accident. The results showed that the elevated air dose rates over the Port of Tokyo and the FDNPS emissions are significantly correlated (log(emission fluxes) = 54.98 x (air dose rates) (R = 0.95, P-value<0.01), and they are also significantly correlated with the Tsukuba deposition fluxes (log(deposition fluxes) = 0.47 + 30.98 (air dose rates) (R = 0.91, P-value<0.01). These results demonstrate the direct impact of the FDNPS emissions on the depositions of radionuclides and the air dose rates over the Port of Tokyo. Over the North Pacific, the correlation equations are log(emission fluxes) = -2.72 + 202.36 x (air dose rates over the northwestern Pacific) (R = 0.40, P-value<0.01), and log(emission fluxes) = -0.55 + 80.19 x (air dose rates over the northeastern Pacific) (R = 0.29, P-value = 0.0424). These results indicate that the resuspension of the deposited radionuclides have become a dominant source in the transport of radionuclides across the North Pacific. Model simulations show underestimated air dose rates during the periods of 22-25 March 2011 and 27-30 March 2011 indicating the lack of mechanisms, such as the resuspension of radionuclides, in the model.
Series
PLOS ONE
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